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Slot: evidence

URI: dismech:slot/evidence Alias: evidence

Applicable Classes

Name Description Modifies Slot
ICDOMorphologyAssignment ICD-O morphology classification assignment for neoplastic diseases no
ComorbidityHypothesis Mechanistic hypothesis for a comorbidity association, with rich text and embe... no
AnimalModel no
AgentLifeCycle no
Definition A diagnostic or phenotype definition for the disease no
Discussion A thread-like record of an open question, controversy, curation todo, emergin... no
ComputationalModel A computational or in-silico model relevant to understanding disease mechanis... no
ProgressionInfo no
EpidemiologyInfo no
Phenotype no
Environmental An environmental factor, exposure, or context relevant to disease no
Prevalence no
HistopathologyFinding A histopathologic finding from microscopic examination of tissue no
CausalEdge A reference to a downstream effect or consequence in a causal relationship yes
ModelingConsideration no
Experiment A structured experiment or protocol-level study design that can be proposed t... yes
IUISAssignment IUIS primary immunodeficiency classification assignment no
Subtype no
Genetic no
Pathophysiology no
ClinicalTrial A clinical trial relevant to treatment or research of a disease yes
SurrogateEndpoint A regulatory surrogate endpoint assertion curated from FDA's surrogate endpoi... no
Finding A key finding or claim extracted from a source (publication or dataset) no
Diagnosis no
HarrisonsChapterAssignment Harrison's internal medicine chapter classification assignment no
ModelMechanismLink Links an experimental model to a specific pathophysiology mechanism node, wit... yes
AgentLifeCycleStage no
ReferenceRange A population reference interval for a clinical laboratory analyte yes
ClassificationAssignment Base class for classification assignments with evidence no
ExperimentalControl A comparator or control condition for an experiment, such as an isogenic wild... no
ChannelopathyAssignment Channelopathy organ system classification assignment no
MechanisticHypothesis Disease-level hypothesis metadata used to organize downstream causal edges in... no
ExternalAssertion An externally curated assertion or registry record relevant to a disease or v... no
PhenotypeContext A context-specific annotation qualifying how a phenotype manifests under part... yes
Variant A genetic variant associated with a disease, including coding and non-coding ... no
MechanisticNosologyAssignment Mechanistic/pathway-based disease classification assignment no
AssociationStatistics Statistical summary with evidence for an association signal no
InfectiousAgent no
Transmission no
Stage no
ExperimentalReadout A structured readout or outcome measured in an experiment no
CriteriaSet A named criteria grouping within a definition no
AssociationSignal An association signal from EHR, registry, or computational sources, optionall... no
ExperimentalModel A disease-relevant non-animal experimental model system no
UpstreamConditionHypothesis Hypothesized upstream condition that may explain both A and B no
BiomarkerReadout Links a biochemical biomarker to a pathograph node that it measures, reflects... yes
LysosomalStorageAssignment Lysosomal storage disease biochemical classification assignment no
ExperimentalPerturbation A structured perturbation, intervention, or exposure used in an experiment no
Treatment no
Dataset A reference to a publicly available omics or phenotype dataset no
TreatmentMechanismTarget Links a treatment to a specific pathophysiology mechanism node it targets yes
DifferentialDiagnosis A disease or condition that presents similarly to the focal disease and must ... no
Inheritance no
Biochemical no

Properties

Type and Range

Property Value
Range EvidenceItem
Domain Of PhenotypeContext, Dataset, ExperimentalModel, Experiment, ExperimentalPerturbation, ExperimentalReadout, ExperimentalControl, ClinicalTrial, ComputationalModel, DifferentialDiagnosis, Subtype, CausalEdge, TreatmentMechanismTarget, ModelMechanismLink, BiomarkerReadout, ReferenceRange, SurrogateEndpoint, ExternalAssertion, Finding, Prevalence, ProgressionInfo, EpidemiologyInfo, Pathophysiology, Phenotype, Biochemical, HistopathologyFinding, Genetic, Environmental, Stage, AgentLifeCycle, AgentLifeCycleStage, AnimalModel, Treatment, InfectiousAgent, Transmission, Diagnosis, Inheritance, Variant, ModelingConsideration, ClassificationAssignment, Definition, CriteriaSet, AssociationSignal, AssociationStatistics, ComorbidityHypothesis, UpstreamConditionHypothesis, MechanisticHypothesis, Discussion

Cardinality and Requirements

Property Value
Recommended Yes
Multivalued Yes

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/monarch-initiative/dismech

Mappings

Mapping Type Mapped Value
self dismech:evidence
native dismech:evidence

LinkML Source

name: evidence
from_schema: https://w3id.org/monarch-initiative/dismech
rank: 1000
alias: evidence
domain_of:
- PhenotypeContext
- Dataset
- ExperimentalModel
- Experiment
- ExperimentalPerturbation
- ExperimentalReadout
- ExperimentalControl
- ClinicalTrial
- ComputationalModel
- DifferentialDiagnosis
- Subtype
- CausalEdge
- TreatmentMechanismTarget
- ModelMechanismLink
- BiomarkerReadout
- ReferenceRange
- SurrogateEndpoint
- ExternalAssertion
- Finding
- Prevalence
- ProgressionInfo
- EpidemiologyInfo
- Pathophysiology
- Phenotype
- Biochemical
- HistopathologyFinding
- Genetic
- Environmental
- Stage
- AgentLifeCycle
- AgentLifeCycleStage
- AnimalModel
- Treatment
- InfectiousAgent
- Transmission
- Diagnosis
- Inheritance
- Variant
- ModelingConsideration
- ClassificationAssignment
- Definition
- CriteriaSet
- AssociationSignal
- AssociationStatistics
- ComorbidityHypothesis
- UpstreamConditionHypothesis
- MechanisticHypothesis
- Discussion
range: EvidenceItem
recommended: true
multivalued: true
inlined: true
inlined_as_list: true