Skip to content

Class: ModelMechanismLink

Links an experimental model to a specific pathophysiology mechanism node, with optional assertion text describing the aspect of the mechanism that the model recapitulates, perturbs, or reads out.

URI: dismech:class/ModelMechanismLink

 classDiagram
    class ModelMechanismLink
    click ModelMechanismLink href "../../classes/ModelMechanismLink/"
      ModelMechanismLink : description

      ModelMechanismLink : evidence





        ModelMechanismLink --> "* _recommended_" EvidenceItem : evidence
        click EvidenceItem href "../../classes/EvidenceItem/"



      ModelMechanismLink : target

Slots

Name Cardinality and Range Description Inheritance
target 1
String
Name of the pathophysiology entry this model is linked to direct
description 0..1
String
Brief assertion-level note describing what facet of the linked mechanism the ... direct
evidence * recommended
EvidenceItem
Evidence that this model is informative for the linked mechanism direct

Usages

used by used in type used
ExperimentalModel modeled_mechanisms range ModelMechanismLink
ComputationalModel modeled_mechanisms range ModelMechanismLink

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/monarch-initiative/dismech

Mappings

Mapping Type Mapped Value
self dismech:ModelMechanismLink
native dismech:ModelMechanismLink

LinkML Source

Direct

name: ModelMechanismLink
description: Links an experimental model to a specific pathophysiology mechanism node,
  with optional assertion text describing the aspect of the mechanism that the model
  recapitulates, perturbs, or reads out.
from_schema: https://w3id.org/monarch-initiative/dismech
slots:
- target
- description
- evidence
slot_usage:
  target:
    name: target
    description: Name of the pathophysiology entry this model is linked to. Must match
      a pathophysiology name in the same disease file.
  description:
    name: description
    description: Brief assertion-level note describing what facet of the linked mechanism
      the model captures or assays.
  evidence:
    name: evidence
    description: Evidence that this model is informative for the linked mechanism

Induced

name: ModelMechanismLink
description: Links an experimental model to a specific pathophysiology mechanism node,
  with optional assertion text describing the aspect of the mechanism that the model
  recapitulates, perturbs, or reads out.
from_schema: https://w3id.org/monarch-initiative/dismech
slot_usage:
  target:
    name: target
    description: Name of the pathophysiology entry this model is linked to. Must match
      a pathophysiology name in the same disease file.
  description:
    name: description
    description: Brief assertion-level note describing what facet of the linked mechanism
      the model captures or assays.
  evidence:
    name: evidence
    description: Evidence that this model is informative for the linked mechanism
attributes:
  target:
    name: target
    description: Name of the pathophysiology entry this model is linked to. Must match
      a pathophysiology name in the same disease file.
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: target
    owner: ModelMechanismLink
    domain_of:
    - CausalEdge
    - TreatmentMechanismTarget
    - ModelMechanismLink
    range: string
    required: true
  description:
    name: description
    description: Brief assertion-level note describing what facet of the linked mechanism
      the model captures or assays.
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: description
    owner: ModelMechanismLink
    domain_of:
    - Descriptor
    - DietaryModification
    - GeneticContext
    - Dataset
    - ExperimentalModel
    - ClinicalTrial
    - ComputationalModel
    - ModelVariable
    - DifferentialDiagnosis
    - Subtype
    - CausalEdge
    - TreatmentMechanismTarget
    - ModelMechanismLink
    - ProteinStructure
    - ExternalAssertion
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - HistopathologyFinding
    - Environmental
    - Disease
    - Stage
    - AgentLifeCycle
    - AgentLifeCycleStage
    - AnimalModel
    - Treatment
    - InfectiousAgent
    - Transmission
    - Assay
    - Diagnosis
    - Inheritance
    - Variant
    - FunctionalEffect
    - Mechanism
    - ModelingConsideration
    - Definition
    - CriteriaSet
    - ConditionDescriptor
    - GOEnrichment
    - ComorbidityHypothesis
    - UpstreamConditionHypothesis
    - MechanisticHypothesis
    range: string
  evidence:
    name: evidence
    description: Evidence that this model is informative for the linked mechanism
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: evidence
    owner: ModelMechanismLink
    domain_of:
    - PhenotypeContext
    - Dataset
    - ExperimentalModel
    - ClinicalTrial
    - ComputationalModel
    - DifferentialDiagnosis
    - Subtype
    - CausalEdge
    - TreatmentMechanismTarget
    - ModelMechanismLink
    - ExternalAssertion
    - Finding
    - Prevalence
    - ProgressionInfo
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - Biochemical
    - HistopathologyFinding
    - Genetic
    - Environmental
    - Stage
    - AgentLifeCycle
    - AgentLifeCycleStage
    - AnimalModel
    - Treatment
    - InfectiousAgent
    - Transmission
    - Diagnosis
    - Inheritance
    - Variant
    - ModelingConsideration
    - ClassificationAssignment
    - Definition
    - CriteriaSet
    - AssociationSignal
    - AssociationStatistics
    - ComorbidityHypothesis
    - UpstreamConditionHypothesis
    - MechanisticHypothesis
    range: EvidenceItem
    recommended: true
    multivalued: true
    inlined: true
    inlined_as_list: true