Class: ModelMechanismLink
Links an experimental model to a specific pathophysiology mechanism node, with optional assertion text describing the aspect of the mechanism that the model recapitulates, perturbs, or reads out.
URI: dismech:class/ModelMechanismLink
classDiagram
class ModelMechanismLink
click ModelMechanismLink href "../../classes/ModelMechanismLink/"
ModelMechanismLink : description
ModelMechanismLink : evidence
ModelMechanismLink --> "* _recommended_" EvidenceItem : evidence
click EvidenceItem href "../../classes/EvidenceItem/"
ModelMechanismLink : target
Slots
| Name | Cardinality and Range | Description | Inheritance |
|---|---|---|---|
| target | 1 String |
Name of the pathophysiology entry this model is linked to | direct |
| description | 0..1 String |
Brief assertion-level note describing what facet of the linked mechanism the ... | direct |
| evidence | * recommended EvidenceItem |
Evidence that this model is informative for the linked mechanism | direct |
Usages
| used by | used in | type | used |
|---|---|---|---|
| ExperimentalModel | modeled_mechanisms | range | ModelMechanismLink |
| ComputationalModel | modeled_mechanisms | range | ModelMechanismLink |
Identifier and Mapping Information
Schema Source
- from schema: https://w3id.org/monarch-initiative/dismech
Mappings
| Mapping Type | Mapped Value |
|---|---|
| self | dismech:ModelMechanismLink |
| native | dismech:ModelMechanismLink |
LinkML Source
Direct
name: ModelMechanismLink
description: Links an experimental model to a specific pathophysiology mechanism node,
with optional assertion text describing the aspect of the mechanism that the model
recapitulates, perturbs, or reads out.
from_schema: https://w3id.org/monarch-initiative/dismech
slots:
- target
- description
- evidence
slot_usage:
target:
name: target
description: Name of the pathophysiology entry this model is linked to. Must match
a pathophysiology name in the same disease file.
description:
name: description
description: Brief assertion-level note describing what facet of the linked mechanism
the model captures or assays.
evidence:
name: evidence
description: Evidence that this model is informative for the linked mechanism
Induced
name: ModelMechanismLink
description: Links an experimental model to a specific pathophysiology mechanism node,
with optional assertion text describing the aspect of the mechanism that the model
recapitulates, perturbs, or reads out.
from_schema: https://w3id.org/monarch-initiative/dismech
slot_usage:
target:
name: target
description: Name of the pathophysiology entry this model is linked to. Must match
a pathophysiology name in the same disease file.
description:
name: description
description: Brief assertion-level note describing what facet of the linked mechanism
the model captures or assays.
evidence:
name: evidence
description: Evidence that this model is informative for the linked mechanism
attributes:
target:
name: target
description: Name of the pathophysiology entry this model is linked to. Must match
a pathophysiology name in the same disease file.
from_schema: https://w3id.org/monarch-initiative/dismech
rank: 1000
alias: target
owner: ModelMechanismLink
domain_of:
- CausalEdge
- TreatmentMechanismTarget
- ModelMechanismLink
range: string
required: true
description:
name: description
description: Brief assertion-level note describing what facet of the linked mechanism
the model captures or assays.
from_schema: https://w3id.org/monarch-initiative/dismech
rank: 1000
alias: description
owner: ModelMechanismLink
domain_of:
- Descriptor
- DietaryModification
- GeneticContext
- Dataset
- ExperimentalModel
- ClinicalTrial
- ComputationalModel
- ModelVariable
- DifferentialDiagnosis
- Subtype
- CausalEdge
- TreatmentMechanismTarget
- ModelMechanismLink
- ProteinStructure
- ExternalAssertion
- EpidemiologyInfo
- Pathophysiology
- Phenotype
- HistopathologyFinding
- Environmental
- Disease
- Stage
- AgentLifeCycle
- AgentLifeCycleStage
- AnimalModel
- Treatment
- InfectiousAgent
- Transmission
- Assay
- Diagnosis
- Inheritance
- Variant
- FunctionalEffect
- Mechanism
- ModelingConsideration
- Definition
- CriteriaSet
- ConditionDescriptor
- GOEnrichment
- ComorbidityHypothesis
- UpstreamConditionHypothesis
- MechanisticHypothesis
range: string
evidence:
name: evidence
description: Evidence that this model is informative for the linked mechanism
from_schema: https://w3id.org/monarch-initiative/dismech
rank: 1000
alias: evidence
owner: ModelMechanismLink
domain_of:
- PhenotypeContext
- Dataset
- ExperimentalModel
- ClinicalTrial
- ComputationalModel
- DifferentialDiagnosis
- Subtype
- CausalEdge
- TreatmentMechanismTarget
- ModelMechanismLink
- ExternalAssertion
- Finding
- Prevalence
- ProgressionInfo
- EpidemiologyInfo
- Pathophysiology
- Phenotype
- Biochemical
- HistopathologyFinding
- Genetic
- Environmental
- Stage
- AgentLifeCycle
- AgentLifeCycleStage
- AnimalModel
- Treatment
- InfectiousAgent
- Transmission
- Diagnosis
- Inheritance
- Variant
- ModelingConsideration
- ClassificationAssignment
- Definition
- CriteriaSet
- AssociationSignal
- AssociationStatistics
- ComorbidityHypothesis
- UpstreamConditionHypothesis
- MechanisticHypothesis
range: EvidenceItem
recommended: true
multivalued: true
inlined: true
inlined_as_list: true