Class: FDASurrogateEndpointCollection

FDA surrogate endpoint table import preserving row-level source provenance

URI: dismech:class/FDASurrogateEndpointCollection

 classDiagram
    class FDASurrogateEndpointCollection
    click FDASurrogateEndpointCollection href "../../classes/FDASurrogateEndpointCollection/"
      SurrogateEndpointCollection <|-- FDASurrogateEndpointCollection
        click SurrogateEndpointCollection href "../../classes/SurrogateEndpointCollection/"

      FDASurrogateEndpointCollection : description

      FDASurrogateEndpointCollection : name

      FDASurrogateEndpointCollection : notes

      FDASurrogateEndpointCollection : retrieved_date

      FDASurrogateEndpointCollection : source_content_current_as_of

      FDASurrogateEndpointCollection : source_url

      FDASurrogateEndpointCollection : source_workbook_sha256

      FDASurrogateEndpointCollection : source_workbook_url

      FDASurrogateEndpointCollection : surrogate_endpoints





        FDASurrogateEndpointCollection --> "1..*" SurrogateEndpoint : surrogate_endpoints
        click SurrogateEndpoint href "../../classes/SurrogateEndpoint/"



      FDASurrogateEndpointCollection : tracked_issues





        FDASurrogateEndpointCollection --> "*" TrackedIssue : tracked_issues
        click TrackedIssue href "../../classes/TrackedIssue/"

Inheritance

• SurrogateEndpointCollection
  • FDASurrogateEndpointCollection

Slots

Name	Cardinality and Range	Description	Inheritance
name	1 String		SurrogateEndpointCollection
description	0..1 String		SurrogateEndpointCollection
source_url	0..1 Uri	URL of the source page for a curated assertion or source collection	SurrogateEndpointCollection
source_workbook_url	0..1 Uri	URL of the source workbook or downloadable data file	SurrogateEndpointCollection
source_workbook_sha256	0..1 String	SHA-256 checksum of the downloaded source workbook used for import	SurrogateEndpointCollection
source_content_current_as_of	0..1 Date	Date shown by the source as the content-current-as-of date	SurrogateEndpointCollection
retrieved_date	0..1 Date	Date on which the source was retrieved for curation	SurrogateEndpointCollection
surrogate_endpoints	1..* SurrogateEndpoint	Curated surrogate endpoint assertions	SurrogateEndpointCollection
tracked_issues	* TrackedIssue	Structured pointers to external tracker issues (e	SurrogateEndpointCollection
notes	0..1 String		SurrogateEndpointCollection

Identifier and Mapping Information

Schema Source

• from schema: https://w3id.org/monarch-initiative/dismech

Mappings

Mapping Type	Mapped Value
self	dismech:FDASurrogateEndpointCollection
native	dismech:FDASurrogateEndpointCollection

LinkML Source

Direct

name: FDASurrogateEndpointCollection
description: FDA surrogate endpoint table import preserving row-level source provenance
from_schema: https://w3id.org/monarch-initiative/dismech
is_a: SurrogateEndpointCollection

Induced

name: FDASurrogateEndpointCollection
description: FDA surrogate endpoint table import preserving row-level source provenance
from_schema: https://w3id.org/monarch-initiative/dismech
is_a: SurrogateEndpointCollection
attributes:
  name:
    name: name
    examples:
    - value: Adolescent Nephronophthisis
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    identifier: true
    alias: name
    owner: FDASurrogateEndpointCollection
    domain_of:
    - ExperimentalModel
    - Experiment
    - ExperimentalPerturbation
    - ExperimentalReadout
    - ExperimentalControl
    - ClinicalTrial
    - ComputationalModel
    - ModelVariable
    - SeverityTier
    - DifferentialDiagnosis
    - Subtype
    - SurrogateEndpointCollection
    - ExternalAssertion
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - Biochemical
    - HistopathologyFinding
    - Genetic
    - Environmental
    - Disease
    - Stage
    - AgentLifeCycleStage
    - Treatment
    - InfectiousAgent
    - Transmission
    - Assay
    - Diagnosis
    - Inheritance
    - Variant
    - Mechanism
    - ModelingConsideration
    - Definition
    - CriteriaSet
    - ComorbidityAssociation
    range: string
    required: true
  description:
    name: description
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: description
    owner: FDASurrogateEndpointCollection
    domain_of:
    - Descriptor
    - DietaryModification
    - GeneticContext
    - Dataset
    - ExperimentalModel
    - Experiment
    - ExperimentalPerturbation
    - ExperimentalReadout
    - ExperimentalControl
    - ClinicalTrial
    - ComputationalModel
    - ModelVariable
    - DifferentialDiagnosis
    - Subtype
    - CausalEdge
    - TreatmentMechanismTarget
    - ModelMechanismLink
    - BiomarkerReadout
    - SurrogateEndpointCollection
    - ProteinStructure
    - ExternalAssertion
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - HistopathologyFinding
    - Environmental
    - Disease
    - Stage
    - AgentLifeCycle
    - AgentLifeCycleStage
    - AnimalModel
    - Treatment
    - InfectiousAgent
    - Transmission
    - Assay
    - Diagnosis
    - Inheritance
    - Variant
    - FunctionalEffect
    - Mechanism
    - ModelingConsideration
    - Definition
    - CriteriaSet
    - ConditionDescriptor
    - GOEnrichment
    - ComorbidityHypothesis
    - UpstreamConditionHypothesis
    - MechanisticHypothesis
    range: string
  source_url:
    name: source_url
    description: URL of the source page for a curated assertion or source collection
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: source_url
    owner: FDASurrogateEndpointCollection
    domain_of:
    - SurrogateEndpoint
    - SurrogateEndpointCollection
    range: uri
  source_workbook_url:
    name: source_workbook_url
    description: URL of the source workbook or downloadable data file
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: source_workbook_url
    owner: FDASurrogateEndpointCollection
    domain_of:
    - SurrogateEndpoint
    - SurrogateEndpointCollection
    range: uri
  source_workbook_sha256:
    name: source_workbook_sha256
    description: SHA-256 checksum of the downloaded source workbook used for import
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: source_workbook_sha256
    owner: FDASurrogateEndpointCollection
    domain_of:
    - SurrogateEndpoint
    - SurrogateEndpointCollection
    range: string
  source_content_current_as_of:
    name: source_content_current_as_of
    description: Date shown by the source as the content-current-as-of date
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: source_content_current_as_of
    owner: FDASurrogateEndpointCollection
    domain_of:
    - SurrogateEndpoint
    - SurrogateEndpointCollection
    range: date
  retrieved_date:
    name: retrieved_date
    description: Date on which the source was retrieved for curation
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: retrieved_date
    owner: FDASurrogateEndpointCollection
    domain_of:
    - SurrogateEndpoint
    - SurrogateEndpointCollection
    range: date
  surrogate_endpoints:
    name: surrogate_endpoints
    description: Curated surrogate endpoint assertions
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: surrogate_endpoints
    owner: FDASurrogateEndpointCollection
    domain_of:
    - SurrogateEndpointCollection
    - Disease
    range: SurrogateEndpoint
    required: true
    multivalued: true
    inlined: true
    inlined_as_list: true
  tracked_issues:
    name: tracked_issues
    description: Structured pointers to external tracker issues (e.g., GitHub ontology
      term requests, schema follow-ups) that provide curation provenance for this
      entry or nested object. Use this in preference to stashing issue URLs inside
      free-text `notes` fields so they can be validated, rendered, and queried consistently.
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: tracked_issues
    owner: FDASurrogateEndpointCollection
    domain_of:
    - SurrogateEndpointCollection
    - Disease
    - TermMapping
    range: TrackedIssue
    multivalued: true
    inlined: true
    inlined_as_list: true
  notes:
    name: notes
    examples:
    - value: Contagious stage where symptoms appear and the bacteria can be spread
        to others.
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: notes
    owner: FDASurrogateEndpointCollection
    domain_of:
    - GeneticContext
    - OnsetDescriptor
    - PhenotypeContext
    - Dataset
    - ExperimentalModel
    - Experiment
    - ExperimentalPerturbation
    - ExperimentalReadout
    - ExperimentalControl
    - ClinicalTrial
    - ComputationalModel
    - ModelVariable
    - DifferentialDiagnosis
    - ReferenceRange
    - SurrogateEndpoint
    - SurrogateEndpointCollection
    - ExternalAssertion
    - TrackedIssue
    - Prevalence
    - ProgressionInfo
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - Biochemical
    - HistopathologyFinding
    - Genetic
    - Environmental
    - Disease
    - Stage
    - AgentLifeCycle
    - AgentLifeCycleStage
    - Treatment
    - Transmission
    - Diagnosis
    - ClassificationAssignment
    - Definition
    - CriteriaSet
    - TermMapping
    - MappingConsistency
    - ComorbidityAssociation
    - AssociationSignal
    - AssociationMetric
    - AssociationStatistics
    - MechanisticHypothesis
    - Discussion
    range: string