Slot: targeting_receptor
The cell-surface receptor or antigen that the targeting ligand binds, bindable to HGNC (e.g., ASGR1 for a GalNAc conjugate, TREM2 for an anti-TREM2-coated nanoparticle). Record the receptor here and the ligand's chemical class in targeting_ligand - they are different facts, and a receptor may be reachable by more than one ligand.
URI: dismech:slot/targeting_receptor
Alias: targeting_receptor
Applicable Classes
| Name |
Description |
Modifies Slot |
| DeliverySystem |
How a treatment's active agent is carried to its target - the formulation pla... |
no |
Properties
Type and Range
Cardinality and Requirements
Schema Source
- from schema: https://w3id.org/monarch-initiative/dismech
Mappings
| Mapping Type |
Mapped Value |
| self |
dismech:targeting_receptor |
| native |
dismech:targeting_receptor |
LinkML Source
name: targeting_receptor
description: The cell-surface receptor or antigen that the targeting ligand binds,
bindable to HGNC (e.g., ASGR1 for a GalNAc conjugate, TREM2 for an anti-TREM2-coated
nanoparticle). Record the receptor here and the ligand's chemical class in targeting_ligand
- they are different facts, and a receptor may be reachable by more than one ligand.
from_schema: https://w3id.org/monarch-initiative/dismech
rank: 1000
alias: targeting_receptor
domain_of:
- DeliverySystem
range: GeneDescriptor
inlined: true