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Class: ReferenceRangeBand

A single graded interpretation band within a reference range, mapping a value interval to a categorical clinical label (e.g., "Normal", "Mild", "Moderate", "Severe", "Critical"). Bands partition the measurement scale so a numeric result can be classified into a clinical category. This expresses the "above value X is mild, above value Y is moderate" style of graded result interpretation that a single normal interval cannot capture.

URI: dismech:class/ReferenceRangeBand

 classDiagram
    class ReferenceRangeBand
    click ReferenceRangeBand href "../../classes/ReferenceRangeBand/"
      ReferenceRangeBand : abnormal_flag





        ReferenceRangeBand --> "0..1" AbnormalFlagEnum : abnormal_flag
        click AbnormalFlagEnum href "../../enums/AbnormalFlagEnum/"



      ReferenceRangeBand : interpretation

      ReferenceRangeBand : lower_bound

      ReferenceRangeBand : name

      ReferenceRangeBand : phenotype_term





        ReferenceRangeBand --> "0..1" PhenotypeDescriptor : phenotype_term
        click PhenotypeDescriptor href "../../classes/PhenotypeDescriptor/"



      ReferenceRangeBand : severity





        ReferenceRangeBand --> "0..1" Any : severity
        click Any href "../../classes/Any/"



      ReferenceRangeBand : unit

      ReferenceRangeBand : upper_bound

Slots

Name Cardinality and Range Description Inheritance
name 1
String		 Category label for this band (e direct
lower_bound 0..1
Float		 Inclusive lower bound of this band's value interval direct
upper_bound 0..1
Float		 Exclusive upper bound of this band's value interval, so adjacent bands sharin... direct
unit 0..1
String		 UCUM unit for this band's bounds direct
abnormal_flag 0..1
AbnormalFlagEnum		 Normal/low/high/critical classification of results in this band, following HL... direct
severity 0..1
String or 
Any or 
SeverityQualifierEnum		 Optional ordinal severity for this band when the category aligns with MILD/MO... direct
phenotype_term 0..1
PhenotypeDescriptor		 Optional HP phenotype that an abnormal result in this band maps to (LOINC2HPO... direct
interpretation 0..1
String		 Free-text clinical interpretation of results that fall in this band direct

Usages

used by used in type used
ReferenceRange interpretation_bands range ReferenceRangeBand

Comments

  • Order bands from lowest to highest value when listing them
  • Bands partition the scale half-open, [lower_bound, upper_bound) — lower_bound inclusive, upper_bound exclusive — so adjacent bands sharing a boundary value do not overlap
  • Omit lower_bound for the lowest (open-below) band
  • Omit upper_bound for the highest (open-above) band
  • Use abnormal_flag to record normal/low/high/critical status per HL7/LOINC
  • Optionally map an abnormal band to an HP phenotype via phenotype_term (LOINC2HPO style)

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/monarch-initiative/dismech

Mappings

Mapping Type Mapped Value
self dismech:ReferenceRangeBand
native dismech:ReferenceRangeBand

LinkML Source

Direct

name: ReferenceRangeBand
description: A single graded interpretation band within a reference range, mapping
  a value interval to a categorical clinical label (e.g., "Normal", "Mild", "Moderate",
  "Severe", "Critical"). Bands partition the measurement scale so a numeric result
  can be classified into a clinical category. This expresses the "above value X is
  mild, above value Y is moderate" style of graded result interpretation that a single
  normal interval cannot capture.
comments:
- Order bands from lowest to highest value when listing them
- Bands partition the scale half-open, [lower_bound, upper_bound) — lower_bound inclusive,
  upper_bound exclusive — so adjacent bands sharing a boundary value do not overlap
- Omit lower_bound for the lowest (open-below) band
- Omit upper_bound for the highest (open-above) band
- Use abnormal_flag to record normal/low/high/critical status per HL7/LOINC
- Optionally map an abnormal band to an HP phenotype via phenotype_term (LOINC2HPO
  style)
from_schema: https://w3id.org/monarch-initiative/dismech
slots:
- name
- lower_bound
- upper_bound
- unit
- abnormal_flag
- severity
- phenotype_term
- interpretation
slot_usage:
  name:
    name: name
    description: Category label for this band (e.g., "Normal", "Mild", "Moderate",
      "Severe", "Critical high").
    required: true
  lower_bound:
    name: lower_bound
    description: Inclusive lower bound of this band's value interval. Omit for an
      open-below band (the lowest tier).
  upper_bound:
    name: upper_bound
    description: Exclusive upper bound of this band's value interval, so adjacent
      bands sharing a boundary value partition cleanly (a result exactly at the boundary
      falls in the next band, whose inclusive lower_bound equals it). Omit for an
      open-above band (the highest tier).
  unit:
    name: unit
    description: UCUM unit for this band's bounds. Usually matches the parent reference
      range; set only if it differs or for standalone clarity.
  abnormal_flag:
    name: abnormal_flag
    description: Normal/low/high/critical classification of results in this band,
      following HL7/LOINC abnormal-flag conventions.
  severity:
    name: severity
    description: Optional ordinal severity for this band when the category aligns
      with MILD/MODERATE/SEVERE grading.
  phenotype_term:
    name: phenotype_term
    description: Optional HP phenotype that an abnormal result in this band maps to
      (LOINC2HPO-style observation-to-phenotype linkage).
  interpretation:
    name: interpretation
    description: Free-text clinical interpretation of results that fall in this band.

Induced

name: ReferenceRangeBand
description: A single graded interpretation band within a reference range, mapping
  a value interval to a categorical clinical label (e.g., "Normal", "Mild", "Moderate",
  "Severe", "Critical"). Bands partition the measurement scale so a numeric result
  can be classified into a clinical category. This expresses the "above value X is
  mild, above value Y is moderate" style of graded result interpretation that a single
  normal interval cannot capture.
comments:
- Order bands from lowest to highest value when listing them
- Bands partition the scale half-open, [lower_bound, upper_bound) — lower_bound inclusive,
  upper_bound exclusive — so adjacent bands sharing a boundary value do not overlap
- Omit lower_bound for the lowest (open-below) band
- Omit upper_bound for the highest (open-above) band
- Use abnormal_flag to record normal/low/high/critical status per HL7/LOINC
- Optionally map an abnormal band to an HP phenotype via phenotype_term (LOINC2HPO
  style)
from_schema: https://w3id.org/monarch-initiative/dismech
slot_usage:
  name:
    name: name
    description: Category label for this band (e.g., "Normal", "Mild", "Moderate",
      "Severe", "Critical high").
    required: true
  lower_bound:
    name: lower_bound
    description: Inclusive lower bound of this band's value interval. Omit for an
      open-below band (the lowest tier).
  upper_bound:
    name: upper_bound
    description: Exclusive upper bound of this band's value interval, so adjacent
      bands sharing a boundary value partition cleanly (a result exactly at the boundary
      falls in the next band, whose inclusive lower_bound equals it). Omit for an
      open-above band (the highest tier).
  unit:
    name: unit
    description: UCUM unit for this band's bounds. Usually matches the parent reference
      range; set only if it differs or for standalone clarity.
  abnormal_flag:
    name: abnormal_flag
    description: Normal/low/high/critical classification of results in this band,
      following HL7/LOINC abnormal-flag conventions.
  severity:
    name: severity
    description: Optional ordinal severity for this band when the category aligns
      with MILD/MODERATE/SEVERE grading.
  phenotype_term:
    name: phenotype_term
    description: Optional HP phenotype that an abnormal result in this band maps to
      (LOINC2HPO-style observation-to-phenotype linkage).
  interpretation:
    name: interpretation
    description: Free-text clinical interpretation of results that fall in this band.
attributes:
  name:
    name: name
    description: Category label for this band (e.g., "Normal", "Mild", "Moderate",
      "Severe", "Critical high").
    examples:
    - value: Adolescent Nephronophthisis
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    identifier: true
    alias: name
    owner: ReferenceRangeBand
    domain_of:
    - ExperimentalModel
    - Experiment
    - ExperimentalPerturbation
    - ExperimentalReadout
    - ExperimentalControl
    - ClinicalTrial
    - ComputationalModel
    - ModelVariable
    - SeverityTier
    - DifferentialDiagnosis
    - Subtype
    - ReferenceRangeBand
    - SurrogateEndpointCollection
    - ExternalAssertion
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - Biochemical
    - HistopathologyFinding
    - ImagingFinding
    - Genetic
    - Environmental
    - Disease
    - Stage
    - AgentLifeCycleStage
    - Treatment
    - InfectiousAgent
    - Transmission
    - Assay
    - Diagnosis
    - Inheritance
    - Variant
    - Mechanism
    - ModelingConsideration
    - Definition
    - CriteriaSet
    - ComorbidityAssociation
    - Grouping
    range: string
    required: true
  lower_bound:
    name: lower_bound
    description: Inclusive lower bound of this band's value interval. Omit for an
      open-below band (the lowest tier).
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: lower_bound
    owner: ReferenceRangeBand
    domain_of:
    - ReferenceRangeBand
    - ReferenceRange
    range: float
  upper_bound:
    name: upper_bound
    description: Exclusive upper bound of this band's value interval, so adjacent
      bands sharing a boundary value partition cleanly (a result exactly at the boundary
      falls in the next band, whose inclusive lower_bound equals it). Omit for an
      open-above band (the highest tier).
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: upper_bound
    owner: ReferenceRangeBand
    domain_of:
    - ReferenceRangeBand
    - ReferenceRange
    range: float
  unit:
    name: unit
    description: UCUM unit for this band's bounds. Usually matches the parent reference
      range; set only if it differs or for standalone clarity.
    examples:
    - value: cm
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: unit
    owner: ReferenceRangeBand
    domain_of:
    - ModelVariable
    - ReferenceRangeBand
    - ReferenceRange
    - EpidemiologyInfo
    range: string
  abnormal_flag:
    name: abnormal_flag
    description: Normal/low/high/critical classification of results in this band,
      following HL7/LOINC abnormal-flag conventions.
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: abnormal_flag
    owner: ReferenceRangeBand
    domain_of:
    - ReferenceRangeBand
    range: AbnormalFlagEnum
  severity:
    name: severity
    description: Optional ordinal severity for this band when the category aligns
      with MILD/MODERATE/SEVERE grading.
    examples:
    - value: Severe
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: severity
    owner: ReferenceRangeBand
    domain_of:
    - Descriptor
    - PhenotypeContext
    - ReferenceRangeBand
    - Phenotype
    range: Any
    any_of:
    - range: SeverityQualifierEnum
    - range: string
  phenotype_term:
    name: phenotype_term
    description: Optional HP phenotype that an abnormal result in this band maps to
      (LOINC2HPO-style observation-to-phenotype linkage).
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: phenotype_term
    owner: ReferenceRangeBand
    domain_of:
    - ExperimentalReadout
    - ReferenceRangeBand
    - Phenotype
    - ImagingFinding
    - LogicalCriterion
    - DifferentiatingMechanism
    range: PhenotypeDescriptor
    inlined: true
  interpretation:
    name: interpretation
    description: Free-text clinical interpretation of results that fall in this band.
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: interpretation
    owner: ReferenceRangeBand
    domain_of:
    - ExperimentalReadout
    - BiomarkerReadout
    - PhenotypeReadout
    - ReferenceRangeBand
    range: string