Slot: regulatory_mechanism

The specific molecular mechanism by which the regulatory variant exerts its effect (e.g., TFBS disruption, enhancer adoption, promoter switching, repressor site loss, novel TFBS creation, heterochromatin spreading).

URI: dismech:slot/regulatory_mechanism Alias: regulatory_mechanism

Applicable Classes

Name	Description	Modifies Slot
FunctionalEffect	Describes the functional consequence of a genetic variant, including regulato...	no

Properties

• Range: String

Identifier and Mapping Information

Schema Source

• from schema: https://w3id.org/monarch-initiative/dismech

Mappings

Mapping Type	Mapped Value
self	dismech:regulatory_mechanism
native	dismech:regulatory_mechanism

LinkML Source

name: regulatory_mechanism
description: The specific molecular mechanism by which the regulatory variant exerts
  its effect (e.g., TFBS disruption, enhancer adoption, promoter switching, repressor
  site loss, novel TFBS creation, heterochromatin spreading).
from_schema: https://w3id.org/monarch-initiative/dismech
rank: 1000
alias: regulatory_mechanism
domain_of:
- FunctionalEffect
range: string