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Slot: regulatory_mechanism

The specific molecular mechanism by which the regulatory variant exerts its effect (e.g., TFBS disruption, enhancer adoption, promoter switching, repressor site loss, novel TFBS creation, heterochromatin spreading).

URI: dismech:slot/regulatory_mechanism Alias: regulatory_mechanism

Applicable Classes

Name Description Modifies Slot
FunctionalEffect Describes the functional consequence of a genetic variant, including regulato... no

Properties

Type and Range

Property Value
Range String
Domain Of FunctionalEffect

Cardinality and Requirements

Property Value

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/monarch-initiative/dismech

Mappings

Mapping Type Mapped Value
self dismech:regulatory_mechanism
native dismech:regulatory_mechanism

LinkML Source

name: regulatory_mechanism
description: The specific molecular mechanism by which the regulatory variant exerts
  its effect (e.g., TFBS disruption, enhancer adoption, promoter switching, repressor
  site loss, novel TFBS creation, heterochromatin spreading).
from_schema: https://w3id.org/monarch-initiative/dismech
rank: 1000
alias: regulatory_mechanism
domain_of:
- FunctionalEffect
range: string