Slot: affected_cell_types
Cell types in which gene expression is specifically gained or lost. Particularly relevant for mLOE variants (modular loss in specific cell types) and GOE variants (ectopic gain in new cell types).
URI: dismech:slot/affected_cell_types Alias: affected_cell_types
Applicable Classes
| Name | Description | Modifies Slot |
|---|---|---|
| FunctionalEffect | Describes the functional consequence of a genetic variant, including regulato... | no |
Properties
-
Range: CellTypeDescriptor
-
Multivalued: True
Identifier and Mapping Information
Schema Source
- from schema: https://w3id.org/monarch-initiative/dismech
Mappings
| Mapping Type | Mapped Value |
|---|---|
| self | dismech:affected_cell_types |
| native | dismech:affected_cell_types |
LinkML Source
name: affected_cell_types
description: Cell types in which gene expression is specifically gained or lost. Particularly
relevant for mLOE variants (modular loss in specific cell types) and GOE variants
(ectopic gain in new cell types).
from_schema: https://w3id.org/monarch-initiative/dismech
rank: 1000
alias: affected_cell_types
domain_of:
- FunctionalEffect
range: CellTypeDescriptor
multivalued: true
inlined: true
inlined_as_list: true