Enum: GHSHealthHazardClassEnum
Health hazard classes of the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (GHS), the international standard implemented in EU law as the CLP Regulation (EC) No 1272/2008 and in the US as the OSHA Hazard Communication Standard.
These ten classes are the GHS health hazards. GHS also defines physical hazard classes (flammability, explosivity, …) and environmental hazard classes (hazardous to the aquatic environment, hazardous to the ozone layer); neither is in scope here, since this axis exists to describe how an agent harms an exposed organism.
Each class is subdivided into numbered categories (and sub-categories) that grade severity — Carcinogenicity 1A/1B/2, acute toxicity 1-5, and so on. The category is not encoded as a permissible value, because the category boundaries are defined per class in terms of class-specific criteria and flattening them into one enum would produce values that only make sense in context. Record the category in the assignment's notes (for example, "Carc. 1A") alongside the class.
URI: dismech:enum/GHSHealthHazardClassEnum
Permissible Values
| Value | Meaning | Description |
|---|---|---|
| ACUTE_TOXICITY | None | Acute toxicity - serious adverse effects, up to lethality, after a single or ... |
| SKIN_CORROSION_IRRITATION | None | Skin corrosion / irritation - irreversible damage to, or reversible inflammat... |
| SERIOUS_EYE_DAMAGE_IRRITATION | None | Serious eye damage / eye irritation - tissue damage or serious physical decay... |
| RESPIRATORY_OR_SKIN_SENSITIZATION | None | Respiratory or skin sensitization - induction of hypersensitivity of the airw... |
| GERM_CELL_MUTAGENICITY | None | Germ cell mutagenicity - heritable gene mutations, including structural and n... |
| CARCINOGENICITY | None | Carcinogenicity - induction of cancer or an increase in cancer incidence afte... |
| REPRODUCTIVE_TOXICITY | None | Reproductive toxicity - adverse effects on sexual function and fertility in a... |
| STOT_SINGLE_EXPOSURE | None | Specific target organ toxicity, single exposure (STOT-SE) - specific, non-let... |
| STOT_REPEATED_EXPOSURE | None | Specific target organ toxicity, repeated exposure (STOT-RE) - specific target... |
| ASPIRATION_HAZARD | None | Aspiration hazard - chemical pneumonia, pulmonary injury or death following a... |
Slots
| Name | Description |
|---|---|
| classification_value |
See Also
Identifier and Mapping Information
Schema Source
- from schema: https://w3id.org/monarch-initiative/dismech
LinkML Source
name: GHSHealthHazardClassEnum
description: 'Health hazard classes of the United Nations Globally Harmonized System
of Classification and Labelling of Chemicals (GHS), the international standard implemented
in EU law as the CLP Regulation (EC) No 1272/2008 and in the US as the OSHA Hazard
Communication Standard.
These ten classes are the GHS *health* hazards. GHS also defines physical hazard
classes (flammability, explosivity, …) and environmental hazard classes (hazardous
to the aquatic environment, hazardous to the ozone layer); neither is in scope here,
since this axis exists to describe how an agent harms an exposed organism.
Each class is subdivided into numbered categories (and sub-categories) that grade
severity — Carcinogenicity 1A/1B/2, acute toxicity 1-5, and so on. The category
is *not* encoded as a permissible value, because the category boundaries are defined
per class in terms of class-specific criteria and flattening them into one enum
would produce values that only make sense in context. Record the category in the
assignment''s ``notes`` (for example, "Carc. 1A") alongside the class.'
from_schema: https://w3id.org/monarch-initiative/dismech
source: https://unece.org/transport/dangerous-goods/ghs-rev10-2023
see_also:
- http://data.europa.eu/eli/reg/2008/1272/oj
rank: 1000
permissible_values:
ACUTE_TOXICITY:
text: ACUTE_TOXICITY
description: Acute toxicity - serious adverse effects, up to lethality, after
a single or short-term oral, dermal or inhalation exposure.
SKIN_CORROSION_IRRITATION:
text: SKIN_CORROSION_IRRITATION
description: Skin corrosion / irritation - irreversible damage to, or reversible
inflammation of, the skin after application of a substance.
SERIOUS_EYE_DAMAGE_IRRITATION:
text: SERIOUS_EYE_DAMAGE_IRRITATION
description: Serious eye damage / eye irritation - tissue damage or serious physical
decay of vision, or reversible ocular changes.
RESPIRATORY_OR_SKIN_SENSITIZATION:
text: RESPIRATORY_OR_SKIN_SENSITIZATION
description: Respiratory or skin sensitization - induction of hypersensitivity
of the airways after inhalation, or an allergic response after skin contact.
The GHS class corresponding to occupational asthma and allergic contact dermatitis.
GERM_CELL_MUTAGENICITY:
text: GERM_CELL_MUTAGENICITY
description: Germ cell mutagenicity - heritable gene mutations, including structural
and numerical chromosome aberrations, in germ cells.
CARCINOGENICITY:
text: CARCINOGENICITY
description: Carcinogenicity - induction of cancer or an increase in cancer incidence
after exposure. Classified independently of, and on different criteria from,
the IARC groups; the two frequently but not always agree, so record both rather
than inferring one from the other.
REPRODUCTIVE_TOXICITY:
text: REPRODUCTIVE_TOXICITY
description: Reproductive toxicity - adverse effects on sexual function and fertility
in adults, and developmental toxicity in the offspring.
STOT_SINGLE_EXPOSURE:
text: STOT_SINGLE_EXPOSURE
description: Specific target organ toxicity, single exposure (STOT-SE) - specific,
non-lethal target-organ effects after one exposure.
STOT_REPEATED_EXPOSURE:
text: STOT_REPEATED_EXPOSURE
description: Specific target organ toxicity, repeated exposure (STOT-RE) - specific
target-organ effects after repeated or prolonged exposure.
ASPIRATION_HAZARD:
text: ASPIRATION_HAZARD
description: Aspiration hazard - chemical pneumonia, pulmonary injury or death
following aspiration of a substance into the trachea and lower respiratory system.