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Enum: EffectModificationAnalysisEnum

How the subgroup difference was established. Ordered roughly from strongest to weakest: a subgroup effect claimed from a post hoc split or from comparing separate studies is a hypothesis, not a finding.

URI: dismech:enum/EffectModificationAnalysisEnum

Permissible Values

Value Meaning Description
PRESPECIFIED_SUBGROUP None A subgroup analysis declared in the trial protocol or analysis plan before un...
POST_HOC_SUBGROUP None A subgroup analysis that was not prespecified
META_ANALYSIS_SUBGROUP None Subgroup analysis or meta-regression across studies in a meta-analysis
CROSS_STRATUM_COMPARISON None Strata that all received the treatment were compared with each other within o...
CROSS_STUDY_COMPARISON None Inferred by comparing separate studies conducted in different populations; th...
OTHER None Any other basis; explain in description

Slots

Name Description
modification_analysis How the subgroup difference was established

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/monarch-initiative/dismech

LinkML Source

name: EffectModificationAnalysisEnum
description: 'How the subgroup difference was established. Ordered roughly from strongest
  to weakest: a subgroup effect claimed from a post hoc split or from comparing separate
  studies is a hypothesis, not a finding.'
from_schema: https://w3id.org/monarch-initiative/dismech
rank: 1000
permissible_values:
  PRESPECIFIED_SUBGROUP:
    text: PRESPECIFIED_SUBGROUP
    description: A subgroup analysis declared in the trial protocol or analysis plan
      before unblinding.
  POST_HOC_SUBGROUP:
    text: POST_HOC_SUBGROUP
    description: A subgroup analysis that was not prespecified.
  META_ANALYSIS_SUBGROUP:
    text: META_ANALYSIS_SUBGROUP
    description: Subgroup analysis or meta-regression across studies in a meta-analysis.
  CROSS_STRATUM_COMPARISON:
    text: CROSS_STRATUM_COMPARISON
    description: Strata that all received the treatment were compared with each other
      within one study, without a separate untreated control for each stratum (for
      example men versus women in a single-arm training study).
  CROSS_STUDY_COMPARISON:
    text: CROSS_STUDY_COMPARISON
    description: Inferred by comparing separate studies conducted in different populations;
      the weakest basis.
  OTHER:
    text: OTHER
    description: Any other basis; explain in description.