Aliases: A20, OTUD7C.
ai-gene-review has this gene at status DRAFT; the description is shown only once the review is complete. Read the draft upstream.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| A20 Haploinsufficiency | causative germline |
mechanism: TNFAIP3 Loss of Function
|
| Celiac Disease | susceptibility | |
| Classic Hodgkin Lymphoma | somatic driver somatic |
mechanism: Mutation-Driven NF-kappaB Activation
|
| Neuropsychiatric Systemic Lupus Erythematosus | susceptibility germline | |
| Splenic Marginal Zone Lymphoma | cooperating somatic | |
| Type I Diabetes | susceptibility germline | |
| Ankylosing Spondylitis |
untyped
GWAS
|
|
| Asthma |
untyped
GWAS
|
|
| Atopic Dermatitis |
untyped
GWAS
|
|
| Crohn Disease |
untyped
GWAS
|
|
| Hodgkin Lymphoma |
untyped
Somatic Loss-of-Function Mutation
somatic
|
mechanism: Mutation-Driven NF-kappaB Activation (Classic HL)
subtype: Classic HL
|
| Multiple Sclerosis |
untyped
GWAS
|
|
| Psoriasis |
untyped
Risk Factor
|
|
| Rheumatoid Arthritis |
untyped
GWAS
|
mechanism: NF-κB Activation
|
| Systemic Lupus Erythematosus |
untyped
GWAS
|
|
| Ulcerative Colitis |
untyped
GWAS
|
mechanism: Mucosal Inflammation
|
| Marginal Zone Lymphoma | no genetic record |
mechanism: Histologic Transformation to Diffuse Large B-Cell Lymphoma
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.