BCL10 - dismech genes

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

Disorder	Relationship	Where the gene appears
Aortic Valve Stenosis	susceptibility
Immunodeficiency 37	causative germline loss of function	mechanism: Biallelic BCL10 Loss of Function
MALT Lymphoma	untyped Recurrent Genetic Lesion
Marginal Zone Lymphoma	no genetic record	mechanism: Deregulation of Marginal Zone B-Cell Differentiation Signalling

ClinGen gene–disease validity · snapshot 2026-10-03 · matched to entries by MONDO

An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.

ClinGen disease	MOI	Classification	dismech entry
immunodeficiency 37 MONDO:0014491	AR	Definitive 2022-12-29	Immunodeficiency 37 causative

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.