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GNAQ

G protein subunit alpha q
4 disorders 2 somatic driver 1 untyped 1 causative 9q21.2 gene with protein product
HGNC:4390MonarchNCBI Gene 2776ENSG00000156052UniProt P50148OMIM 600998

Aliases: G-ALPHA-q, GAQ.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

DisorderRelationshipWhere the gene appears
Meningeal Melanocytoma somatic driver somatic
mechanism: G-alpha-q Pathway Activation
Ocular Melanoma somatic driver somatic
mechanism: Gq/G11 Alpha Subunit Activating Mutation
subtype: Uveal Melanoma
scoped to subtype: Uveal Melanoma
Sturge-Weber Syndrome causative somatic
mechanism: Somatic GNAQ Activating Mutation
Nevus of Ota untyped
Causative
somatic
mechanism: Mosaic GNAQ-GNA11 Melanocyte Signaling
Mechanism modules · computed from kb/

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.