Aliases: FIX.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Hemophilia |
untyped
Pathogenic Variants
|
mechanism: Intrinsic Tenase Subunit Deficiency
subtype: Hemophilia B; Hemophilia B Leyden
|
| Hemophilia B |
untyped
Pathogenic Variants
|
mechanism: Factor IX Deficiency; Leyden promoter dysfunction
|
| Chlorophacinone Poisoning | no genetic record |
mechanism: Functional Deficiency of Coagulation Factors II, VII, IX and X; Impaired Gamma-Carboxylation of Vitamin K-Dependent Clotting Factors
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| thrombophilia, X-linked, due to factor 9 defect MONDO:0010432 | XL | Limited 2023-11-06 |
no dismech entry |
| hemophilia B MONDO:0010604 | XL | Definitive 2019-05-22 |
Hemophilia
untyped
Hemophilia B
untyped
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.