Aliases: Mi-2b, Mi2-BETA.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Dermatomyositis |
untyped
Associated
|
|
| Sifrim-Hitz-Weiss syndrome | untyped |
mechanism: CHD4/NuRD chromatin remodeling dysfunction; Impaired NuRD-dependent cortical neurogenesis; NuRD-dependent cardiac transcriptional repression defect
|
| Ewing Sarcoma | no genetic record |
mechanism: CHD4 Chromatin Architecture Maintenance; NuRD-LSD1 Transcriptional Repression
|
| Holt-Oram syndrome | no genetic record |
mechanism: Cofactor and Chromatin Remodeling Dysfunction
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| syndromic intellectual disability MONDO:0000508 | AD | Definitive 2023-04-19 |
no dismech entry |
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.