TNFRSF13B

TNF receptor superfamily member 13B

2 disorders 1 susceptibility 1 modifier 17p11.2 gene with protein product

HGNC:18153 Monarch NCBI Gene 23495 ENSG00000240505 UniProt O14836 OMIM 604907

Aliases: TACI, CD267, IGAD2.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

Disorder	Relationship	Where the gene appears
Common Variable Immunodeficiency	susceptibility	mechanism: BAFF/APRIL Receptor Signaling Deficiency subtype: CVID2 scoped to subtype: CVID2
Selective IgA Deficiency	modifier

ClinGen gene–disease validity · snapshot 2026-10-03 · matched to entries by MONDO

An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.

ClinGen disease	MOI	Classification	dismech entry
immunodeficiency, common variable, 2 MONDO:0009413	AR	Definitive 2021-01-20	Common Variable Immunodeficiency susceptibility

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.