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STS

steroid sulfatase
3 disorders 1 modifier 1 untyped 1 causative Xp22.31 gene with protein product
HGNC:11425MonarchNCBI Gene 412ENSG00000101846UniProt P08842OMIM 300747

Previous symbols: ARSC1. Aliases: ARSC.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

DisorderRelationshipWhere the gene appears
Ichthyosis Vulgaris modifier
Pre-Descemet Corneal Dystrophy causative germline loss of function
mechanism: Loss of Steroid Sulfatase Function
subtype: XLI-Associated Deep Corneal Deposits
scoped to subtype: XLI-Associated Deep Corneal Deposits
Inherited Ichthyosis untyped
Causative steroid sulfatase deficiency in X-linked ichthyosis
mechanism: Epidermal Lipid Metabolism Defect
subtype: X-Linked Ichthyosis
scoped to subtype: X-Linked Ichthyosis
Mechanism modules · computed from kb/

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.