SGCD

sarcoglycan delta

3 disorders 3 untyped 5q33.2-q33.3 gene with protein product

HGNC:10807 Monarch NCBI Gene 6444 ENSG00000170624 UniProt Q92629 OMIM 601411

Aliases: DAGD, LGMD2F, CMD1L.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

Disorder	Relationship	Where the gene appears
Autosomal Recessive Limb-Girdle Muscular Dystrophy	untyped	mechanism: Sarcolemmal Instability and Failed Membrane Repair subtype: LGMDR6 scoped to subtype: LGMDR6
Dilated Cardiomyopathy 1L	untyped germline dominant negative CLINGEN: limited	mechanism: Heterozygous SGCD Variant
Sarcoglycanopathy	untyped	mechanism: Sarcoglycan-Sarcospan Subcomplex Assembly at the Sarcolemma subtype: SGCD scoped to subtype: SGCD

ClinGen gene–disease validity · snapshot 2026-10-03 · matched to entries by MONDO

An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.

ClinGen disease	MOI	Classification	dismech entry
dilated cardiomyopathy 1L MONDO:0011702	AD	Limited 2026-03-04	Dilated Cardiomyopathy 1L untyped
autosomal recessive limb-girdle muscular dystrophy MONDO:0015152	AR	Definitive 2024-11-14	Autosomal Recessive Limb-Girdle Muscular Dystrophy untyped

Mechanism modules · computed from kb/

sarcolemmal_fragility_myofiber_necrosis via Autosomal Recessive Limb-Girdle Muscular Dystrophy

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.