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Familial Vesicoureteral Reflux

Addendum — resolved ontology identifiers

2026-08-01
Claude Code MONDO:0017329 Model: claude-haiku-4-5-20251001, claude-opus-5[1m]

The two OAK verification jobs I had backgrounded have now returned, so four identifiers I flagged [UNVERIFIED] in §12 and Appendix B are resolved:

Addendum — resolved ontology identifiers

CHEBI (therapeutic agents for prophylaxis)

Table (click to expand)
Agent CHEBI ID Canonical label (verified)
Trimethoprim CHEBI:45924 trimethoprim
Sulfamethoxazole CHEBI:9332 sulfamethoxazole
Cephalexin CHEBI:3534 cephalexin — note the label is cephalexin, not cefalexin; CHEBI:135750 is the distinct prodrug cefalexin pivoxil
Nitrofurantoin CHEBI:71415 nitrofurantoin (already verified)
Amoxicillin CHEBI:2676 amoxicillin (already verified)

So the RIVUR/PREDICT regimen is curated as therapeutic_agent with two entries — CHEBI:45924 + CHEBI:9332 — under treatment_term: NCIT:C15986.

NCIT (treatment action terms)

  • NCIT:C51993 Antibiotic Prophylaxis — definition "Administration of antibiotics with the intent of preventing bacterial infection." Parent is NCIT:C15843 Preventive Intervention, which is not under NCIT:C25218 (Clinical Intervention or Procedure). This term will therefore likely fail the dismech TreatmentTerm dynamic-enum check. Use NCIT:C15986 Pharmacotherapy as treatment_term and carry the prophylactic intent in the treatment name/description.
  • NCIT:C101242 Reimplantation — is_a NCIT:C64982 Therapeutic Surgical Procedure, so it is reachable from NCIT:C25218 and is safe for open ureteral reimplantation (with therapeutic_modality: SURGERY).
  • NCIT:C15240 Genetic Counseling and NCIT:C15986 Pharmacotherapy — labels confirmed as used in §12/§13.

Everything else flagged in Appendix B remains unverified and should still be resolved before those items enter a KB entry.