Down_syndrome

Disorder

• Name: Down_syndrome
• Category: Genetic
• Existing deep-research providers: falcon
• Existing evidence reference count in YAML: 15

Key Pathophysiology Nodes

• Extra Chromosome 21
• Interferon Hyperactivation
• Neurodevelopmental Alterations
• Deep research literature mapping

Citation Inventory (for evidence mapping)

• DOI:10.1016/j.isci.2025.113130
• DOI:10.1038/s41583-024-00866-2
• DOI:10.1101/2025.06.30.662385
• DOI:10.1126/sciadv.adg6218
• DOI:10.3390/cells13242037
• DOI:10.7554/elife.89763.3