Dental Caries deep-research fallback

This fallback research note was added while repairing the older conflicting PR #1370. No provider-generated deep-research artifact was present on the branch, so the review fix was bounded to the cached references already cited by the entry and the concrete open review comments.

Scope checked

• Ecological-plaque-hypothesis framing: PMID:12624191 and PMID:29195050 support low-pH selection, oral microbiome dysbiosis, and self-reinforcing cariogenic biofilm ecology.
• Biofilm virulence and species breadth: PMID:40933845 supports S. mutans glucosyltransferase, glucan-binding, and two-component virulence genes. The YAML now frames this as mutans-streptococci / cariogenic-biofilm biology rather than implying that extracellular glucan biosynthesis is restricted to S. mutans alone.
• Enamel chemistry: PMID:28540937 and PMID:17208642 support caries as phasic demineralization and remineralization of dental hard tissues. The acid-mediated node now models reduced apatite directly instead of binding acid dissolution to decreased tooth-mineralization GO.
• Probiotic therapy: PMID:40995678 contains a direct clinical-trial summary for reduced S. mutans counts and caries incidence with probiotic lozenges, gums, and dairy products; the treatment evidence was updated to quote that outcome text.

Remaining limitations

This is not a broad new literature expansion. It documents the targeted review-fix scope needed to make the older Dental Caries branch auditable without adding uncited claims or hand-edited reference caches.