Previous symbols: PRSS11. Aliases: HtrA, IGFBP5-protease, ARMD7.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Age-Related Macular Degeneration | susceptibility germline |
mechanism: 10q26 ARMS2/HTRA1 Genetic Susceptibility
|
| CADASIL Type 2 | causative germline |
mechanism: HTRA1 Serine Protease Loss of Function
subtype: CARASIL; HTRA1-CSVD
|
Identity from HGNC (snapshot 2026-10-24). Page layers are described in the gene pages documentation.