Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Classic Hodgkin Lymphoma | somatic driver somatic |
mechanism: Mutation-Driven MHC Class I Loss
|
| Hypercatabolic Hypoproteinemia | causative | |
| Primary Central Nervous System Lymphoma | causative somatic | |
| Hodgkin Lymphoma |
untyped
Somatic Mutation
somatic
|
mechanism: Mutation-Driven MHC Class I Loss (Classic HL)
subtype: Classic HL
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| hypoproteinemia, hypercatabolic MONDO:0009434 | AR | Limited 2024-04-18 |
Hypercatabolic Hypoproteinemia
causative
|
| amyloidosis, hereditary systemic 6 MONDO:0971010 | AD | Limited 2026-05-06 |
no dismech entry |
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.