Previous symbols: OPRS1. Aliases: S1R, SIGMA1R, SR-BP1.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Juvenile Amyotrophic Lateral Sclerosis | causative |
mechanism: Sigma-1 Receptor Mislocalization and ER Stress Vulnerability
subtype: ALS16
scoped to subtype: ALS16
|
| Distal Hereditary Motor Neuronopathy, Autosomal Recessive | untyped |
scoped to subtype: dSMA2
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.