Aliases: FXR, RIP14, HRR1, HRR-1.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Progressive Familial Intrahepatic Cholestasis | causative germline |
mechanism: Canalicular Bile Formation Defect; FXR Bile Acid Sensing and Transcriptional Failure
subtype: PFIC5
scoped to subtype: PFIC5
|
| Intrahepatic Cholestasis of Pregnancy | no genetic record |
mechanism: Genetic and Hormonal Susceptibility of Hepatobiliary Transport
|
| Primary Bile Acid Malabsorption | no genetic record |
mechanism: Loss of FXR-FGF19 Signalling from the Ileum
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.