NDRG1 - dismech genes

NDRG1

N-myc downstream regulated 1

2 disorders 1 untyped 1 causative 8q24.22 gene with protein product

Previous symbols: CAP43. Aliases: DRG1, RTP, TDD5, NDR1.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

Disorder	Relationship	Where the gene appears
Charcot-Marie-Tooth disease type 4D	causative germline loss of function	mechanism: Biallelic NDRG1 Loss-of-Function Variant
Charcot-Marie-Tooth Disease Type 4	untyped Causal	mechanism: Impaired Axon-Glia Interaction subtype: CMT4D scoped to subtype: CMT4D

Mechanism modules · computed from kb/

peripheral_axonal_degeneration via Charcot-Marie-Tooth disease type 4D
schwann_cell_myelin_maintenance via Charcot-Marie-Tooth Disease Type 4

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.