Previous symbols: NARS. Aliases: AsnRS.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Neurodevelopmental Disorder with Microcephaly, Impaired Language, and Gait Abnormalities | causative partial loss of function |
mechanism: Biallelic Hypomorphic NARS1 Variants
|
| Antisynthetase Syndrome |
untyped
Autoantigen
|
mechanism: Loss of Tolerance to Aminoacyl-tRNA Synthetases
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| neurodevelopmental disorder with microcephaly, impaired language, epilepsy, and gait abnormalities MONDO:0030837 | AD | Moderate 2024-03-06 |
no dismech entry |
| neurodevelopmental disorder with microcephaly, impaired language, and gait abnormalities MONDO:0100348 | AR | Moderate 2024-03-06 |
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.