Previous symbols: CDC21. Aliases: CDC54, hCdc21, P1-Cdc21, MGC33310.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Familial Glucocorticoid Deficiency | causative germline |
mechanism: Adrenocortical Replicative Stress and Impaired Steroidogenic Cell Differentiation
|
| Natural Killer Cell and Glucocorticoid Deficiency with DNA Repair Defect | causative germline partial loss of function |
mechanism: Hypomorphic MCM4 Deficiency
|
| X-linked Reticulate Pigmentary Disorder | no genetic record |
mechanism: MCM4 Depletion
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| primary immunodeficiency with natural-killer cell deficiency and adrenal insufficiency MONDO:0012383 | AR | Moderate 2023-08-17 |
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.