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MAF

MAF bZIP transcription factor
2 disorders 1 untyped 1 causative 16q23.2 gene with protein product
HGNC:6776MonarchNCBI Gene 4094ENSG00000178573UniProt O75444OMIM 177075

Aliases: c-MAF.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

DisorderRelationshipWhere the gene appears
Cataract 21 Multiple Types causative germline
mechanism: Impaired MAF Transactivation of Crystallin and Lens Genes; Pathogenic MAF Variant
Ayme-Gripp syndrome untyped
Pathogenic missense variants impairing phosphorylation-dependent turnover
mechanism: Dysregulated MAF-dependent transcriptional programs; Impaired GSK3-mediated MAF phosphorylation; Impaired MAF ubiquitination and proteasomal degradation

Identity from HGNC (snapshot 2026-10-24). Page layers are described in the gene pages documentation.