Browse All / Genes / LRP6

LRP6

LDL receptor related protein 6
2 disorders 2 untyped 12p13.2 gene with protein product
HGNC:6698MonarchNCBI Gene 4040ENSG00000070018UniProt O75581OMIM 603507

Aliases: ADCAD2.

Normal function · from ai-gene-review (O75581, commit 79fe13b38970) · AI-generated, not KB evidence

ai-gene-review has this gene at status DRAFT; the description is shown only once the review is complete. Read the draft upstream.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

DisorderRelationshipWhere the gene appears
Coronary Artery Congenital Malformation untyped
Candidate Susceptibility Gene
Tooth Agenesis untyped
Pathogenic Variants
mechanism: WNT/beta-catenin Signaling Deficiency
subtype: LRP6-related
scoped to subtype: LRP6-related

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.