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LPL

lipoprotein lipase
2 disorders 2 causative 8p21.3 gene with protein product
HGNC:6677MonarchNCBI Gene 4023ENSG00000175445UniProt P06858OMIM 609708

Previous symbols: LIPD.

Normal function · from ai-gene-review (P06858, commit 79fe13b38970) · AI-generated, not KB evidence

ai-gene-review has this gene at status DRAFT; the description is shown only once the review is complete. Read the draft upstream.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

DisorderRelationshipWhere the gene appears
Familial Chylomicronemia Syndrome causative
mechanism: Lipoprotein Lipase Deficiency
subtype: FCS-LPL
scoped to subtype: FCS-LPL
Hyperlipidemia causative
mechanism: Impaired Lipoprotein Lipase Activity and ApoC-III Dysregulation

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.