Aliases: C-Lmod.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Dilated Cardiomyopathy 2G |
causative
germline
loss of function
CLINGEN: definitive
|
mechanism: Biallelic LMOD2 Loss-of-Function Variant
treatment: Experimental steric blockade of LMOD2 nonsense-mediated decay
|
| Dilated Cardiomyopathy |
untyped
Pathogenic Variants
|
mechanism: Sarcomeric and Cytoskeletal Dysfunction
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| cardiomyopathy, dilated, 2G MONDO:0030887 | AR | Definitive 2026-03-04 |
Dilated Cardiomyopathy 2G
causative
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.