KCNQ4

potassium voltage-gated channel subfamily Q member 4

2 disorders 1 untyped 1 susceptibility 1p34.2 gene with protein product

HGNC:6298 Monarch NCBI Gene 9132 ENSG00000117013 UniProt P56696 OMIM 603537

Previous symbols: DFNA2. Aliases: Kv7.4.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

Disorder	Relationship	Where the gene appears
Noise Induced Hearing Loss	susceptibility
Autosomal Dominant Nonsyndromic Hearing Loss 2A	untyped Causal	treatment: Allele-Preferential Antisense Oligonucleotide Knockdown

ClinGen gene–disease validity · snapshot 2026-10-03 · matched to entries by MONDO

An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.

ClinGen disease	MOI	Classification	dismech entry
nonsyndromic genetic hearing loss MONDO:0019497	AD	Definitive 2017-11-21	no dismech entry

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.