Aliases: JTK10.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Acute Erythroid Leukemia | cooperating somatic |
mechanism: EPOR/JAK2/STAT5 Signaling Amplification
|
| Acute Megakaryoblastic Leukemia | biomarker somatic |
mechanism: Adult Adverse Genomic Landscape and Therapy Resistance
scoped to subtype: Adult AMKL
|
| Classic Hodgkin Lymphoma | somatic driver somatic |
mechanism: Mutation-Driven JAK/STAT Activation
|
| High Altitude Pulmonary Edema | susceptibility | |
| Immunodeficiency 118 | modifier germline |
mechanism: Reduced JAK2 Protein
|
| Pyoderma Gangrenosum | susceptibility | |
| Budd-Chiari Syndrome |
untyped
Somatic prothrombotic risk factor
|
mechanism: Systemic Prothrombotic Predisposition
|
| Essential Thrombocythemia |
untyped
Somatic Activating Mutations
|
|
| Monkeypox |
untyped
Downregulated during infection
|
|
| Myeloproliferative Neoplasm, Unclassifiable |
untyped
Somatic activating variants
|
|
| Polycythemia Vera |
untyped
Somatic Activating Mutations
|
|
| Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma |
untyped
Recurrent somatic driver event
somatic
|
mechanism: JAK2-SH2B3 Axis Deregulation
|
| Primary Myelofibrosis |
untyped
Somatic Activating Mutations
|
|
| Hodgkin Lymphoma | no genetic record somatic |
mechanism: Mutation-Driven JAK/STAT Activation (Classic HL)
subtype: Classic HL
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.