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IL12RB1

interleukin 12 receptor subunit beta 1
3 disorders 1 untyped 1 susceptibility 1 causative 19p13.11 gene with protein product
HGNC:5971MonarchNCBI Gene 3594ENSG00000096996UniProt P42701OMIM 601604

Previous symbols: IL12RB. Aliases: CD212.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

DisorderRelationshipWhere the gene appears
Invasive Non-Typhoidal Salmonellosis susceptibility
Mendelian Susceptibility To Mycobacterial Diseases Due To Complete IL12RB1 Deficiency causative germline loss of function
mechanism: IL12RB1 Loss of Function
Coccidioidomycosis untyped
IL-12 receptor subunit; deficiency impairs IFN-gamma production
mechanism: Th1/Th17 cell-mediated adaptive immunity
Mechanism modules · computed from kb/

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.