Aliases: JTK13, CD221, IGFIR, MGC18216, IGFR.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Growth Hormone Insensitivity Syndrome | causative germline |
mechanism: Reduced IGF-1 Production and Action
subtype: IGF1 Resistance
scoped to subtype: IGF1 Resistance
|
| Polycystic Ovary Syndrome |
untyped
Risk Factor
|
mechanism: Population-Specific Metabolic vs. Inflammatory Dysregulation
|
| Tall Stature-Intellectual Disability-Renal Anomalies Syndrome |
untyped
Contributes to disease susceptibility
|
mechanism: Distal 15q Dosage Gain; IGF1R Overexpression and Growth Signaling Activation
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.