Browse All / Genes / HOXD13

HOXD13

homeobox D13
5 disorders 3 causative 2 no genetic record 2q31.1 gene with protein product
HGNC:5136MonarchNCBI Gene 3239ENSG00000128714UniProt P35453OMIM 142989

Previous symbols: HOX4I, SPD.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

DisorderRelationshipWhere the gene appears
Brachydactyly Type D causative germline
mechanism: Altered HOXD13 Homeodomain DNA Binding
Brachydactyly Type E1 causative germline
mechanism: Altered HOXD13 Homeodomain Function
Mesomelic Dysplasia, Kantaputra Type causative
mechanism: Copy-Number Rearrangement at the HOXD Locus
Ewing Sarcoma no genetic record
mechanism: HOXD13-Driven Mesenchymal Plasticity
Split Hand-Foot Malformation no genetic record
mechanism: Disrupted Wnt-BMP-FGF Signaling and Central Ray Loss
subtype: SHFM5
Mechanism modules · computed from kb/

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.