Aliases: G-ALPHA-o.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Early-Infantile Developmental and Epileptic Encephalopathy | causative de novo | |
| GNAO1-Related Developmental and Epileptic Encephalopathy | causative de novogermline loss of function |
mechanism: GNAO1 Pathogenic Variant (Gao)
subtype: DEE17; NEDIM
dataset: geo:GSE241258; geo:GSE263736
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| movement disorder MONDO:0005395 | AD | Definitive 2019-02-19 |
no dismech entry |
| genetic developmental and epileptic encephalopathy MONDO:0100062 | AD | Definitive 2018-12-18 |
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.