Previous symbols: FOLR. Aliases: FRα.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| FOLR1-Related Cerebral Folate Transport Deficiency | causative | |
| Fetal Valproate Syndrome | no genetic record |
mechanism: Folate Receptor Antagonism
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| neurodegenerative syndrome due to cerebral folate transport deficiency MONDO:0013110 | AR | Definitive 2017-10-20 |
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.