DNAH11

dynein axonemal heavy chain 11

2 disorders 1 causative 1 untyped 7p15.3 gene with protein product

HGNC:2942 Monarch NCBI Gene 8701 ENSG00000105877 UniProt Q96DT5 OMIM 603339

Aliases: Dnahc11, DPL11, CILD7, DNAHC11, DNAHBL, DNHBL.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

Disorder	Relationship	Where the gene appears
Primary Ciliary Dyskinesia 7	causative germline loss of function CLINGEN: definitive	mechanism: Biallelic DNAH11 Loss of Function
Primary_Ciliary_Dyskinesia	untyped Pathogenic Variants	mechanism: Ciliary Dysfunction; Nodal Ciliary Motility Defect subtype: CILD7 scoped to subtype: CILD7

ClinGen gene–disease validity · snapshot 2026-10-03 · matched to entries by MONDO

An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.

ClinGen disease	MOI	Classification	dismech entry
primary ciliary dyskinesia 7 MONDO:0012748	AR	Definitive 2021-10-25	Primary Ciliary Dyskinesia 7 causative Primary_Ciliary_Dyskinesia untyped

Mechanism modules · computed from kb/

ciliopathy_dysfunction via Primary_Ciliary_Dyskinesia

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.