DAND5

DAN domain BMP antagonist family member 5

2 disorders 1 no genetic record 1 untyped 19p13.13 gene with protein product

HGNC:26780 Monarch NCBI Gene 199699 ENSG00000179284 UniProt Q8N907 OMIM 609068

Aliases: FLJ38607, CKTSF1B3, DANTE, GREM3, CER2, DTE, Coco.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

Disorder	Relationship	Where the gene appears
Visceral heterotaxy	untyped Recessive monogenic cause
Primary_Ciliary_Dyskinesia	no genetic record	mechanism: Loss of Asymmetric Flow-Sensing and Nodal Signaling

ClinGen gene–disease validity · snapshot 2026-10-03 · matched to entries by MONDO

An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.

ClinGen disease	MOI	Classification	dismech entry
congenital heart disease MONDO:0005453	UD	Disputed 2024-06-10	Congenital Heart Disease not named

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.