Previous symbols: KIAA1546. Aliases: FLJ20032.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Acute Erythroid Leukemia | cooperating somatic | |
| Acute Megakaryoblastic Leukemia | biomarker somatic |
mechanism: Adult Adverse Genomic Landscape and Therapy Resistance
scoped to subtype: Adult AMKL
|
| Aggressive NK-cell Leukemia | unknown somaticunknown |
mechanism: Epigenetic-Regulator Alterations
|
| Blastic Plasmacytoid Dendritic Cell Neoplasm | somatic driver somatic loss of function |
mechanism: TET2 Loss in a Hematopoietic Precursor; UV-Selected Survival of TET2-Mutant pDC Precursors in Sun-Exposed Skin
|
| Chronic Myelomonocytic Leukemia | somatic driver somatic | |
| Myelodysplastic Syndrome | somatic driver somatic | |
| Peripheral T-Cell Lymphoma |
untyped
Recurrent Somatic Mutation
|
scoped to subtype: TFH Angioimmunoblastic-Type
|
| Polycythemia Vera |
untyped
Somatic Co-mutation
|
|
| Primary Myelofibrosis |
untyped
Somatic Loss-of-Function Mutations
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| pulmonary arterial hypertension MONDO:0015924 | AD | Moderate 2025-02-24 |
Pulmonary_hypertension
not named
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.