Browse All / Genes / CYP11B1

CYP11B1

cytochrome P450 family 11 subfamily B member 1
3 disorders 1 causative 1 no genetic record 1 untyped 8q24.3 gene with protein product
HGNC:2591MonarchNCBI Gene 1584ENSG00000160882UniProt P15538OMIM 610613

Previous symbols: CYP11B. Aliases: P450C11, FHI, CPN1.

Normal function · from ai-gene-review (P15538, commit 79fe13b38970) · AI-generated, not KB evidence

ai-gene-review has this gene at status INITIALIZED; the description is shown only once the review is complete. Read the draft upstream.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

DisorderRelationshipWhere the gene appears
Congenital Adrenal Hyperplasia causative germline
mechanism: CYP11B1 11-Beta-Hydroxylase Deficiency
subtype: 11B-OHD
scoped to subtype: 11B-OHD
Familial hyperaldosteronism type I untyped
Fusion gene component
mechanism: ACTH-regulated aldosterone synthase expression; CYP11B1-CYP11B2 chimeric gene formation
familial hyperaldosteronism no genetic record
mechanism: ACTH-regulated aldosterone synthase expression
subtype: Type I

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.