Previous symbols: TRMT. Aliases: FLJ10140, MTO2, MTU1.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Aminoglycoside-Induced Hearing Loss | modifier |
mechanism: Reduced TRMU-Dependent tRNA Thiolation
|
| TRMU-Related Acute Infantile Liver Failure | causative |
mechanism: Biallelic TRMU Loss of Function
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| Leigh syndrome MONDO:0009723 | AR | Moderate 2021-01-21 |
Leigh Syndrome
not named
|
| mitochondrial disease MONDO:0044970 | AR | Definitive 2024-05-23 |
no dismech entry |
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.