Aliases: MYOP.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| MYPN-Related Cardiomyopathy | causative germline unknown |
mechanism: MYPN Variant Altering Myopalladin
subtype: CMD1KK; CMH22; CMR4
|
| Nemaline Myopathy | causative |
mechanism: Z-Disc Scaffold Loss (MYPN)
subtype: NEM11
|
| Restrictive Cardiomyopathy | causative | |
| Dilated Cardiomyopathy |
untyped
Pathogenic Variants
|
mechanism: Sarcomeric and Cytoskeletal Dysfunction
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| hypertrophic cardiomyopathy MONDO:0005045 | AD | Disputed 2023-06-14 |
Hypertrophic Cardiomyopathy
not named
|
| dilated cardiomyopathy 1KK MONDO:0014100 | AD | Limited 2026-03-04 |
MYPN-Related Cardiomyopathy
causative
|
| MYPN-related myopathy MONDO:0015023 | AR | Definitive 2020-06-17 |
Nemaline Myopathy
causative
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.