Aliases: KIAA1858, Zfp469.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Keratoconus | susceptibility | |
| Brittle Cornea Syndrome |
untyped
Biallelic ZNF469 variants cause BCS1. ZNF469 was independently identified as a quantitative trait locus for central corneal thickness, which is consistent with a dose-sensitive role in setting corneal stromal thickness.
|
mechanism: Loss of PRDM5 or ZNF469 Transcriptional Regulator Function
subtype: BCS1
scoped to subtype: BCS1
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.