Aliases: K35.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| CDK8-Related Disorder |
causative
germline
G2P: definitive
|
mechanism: CDK8 Coding Missense Substitutions; Reduced CDK8 Kinase Activity
|
| Mediator Complex Neurodevelopmental Disorder |
untyped
Causative
|
mechanism: CDK8 Kinase Module Dysfunction
subtype: CDK8
scoped to subtype: CDK8
|
| MED13 Syndrome | no genetic record |
mechanism: CKM hinge anchoring by MED13
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.