Previous symbols: IGB. Aliases: B29, Ig-beta, Igbeta.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Autosomal Agammaglobulinemia | causative germline |
mechanism: Ig-Beta Deficiency
subtype: AGM6
scoped to subtype: AGM6
|
| Primary Central Nervous System Lymphoma | causative somatic | |
| Primary_Tonsillar_Lymphoma | no genetic record |
mechanism: Malignant B-cell Proliferation (Activated B-cell Type)
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| agammaglobulinemia 6, autosomal recessive MONDO:0012987 | AR | Definitive 2021-01-26 |
Autosomal Agammaglobulinemia
causative
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.