Browse All / Genes / TRIM28

TRIM28

tripartite motif containing 28
2 disorders 1 causative 1 risk factor 19q13.43 gene with protein product
HGNC:16384MonarchNCBI Gene 10155ENSG00000130726UniProt Q13263OMIM 601742

Aliases: TIF1B, KAP1, TF1B, RNF96, PPP1R157, KAP-1, TIF1-beta, TIF1beta.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

DisorderRelationshipWhere the gene appears
TRIM28-Related Wilms Tumor Predisposition causative germlinesomatic loss of function
mechanism: Biallelic TRIM28 Loss in Nephrogenic Precursors; Germline TRIM28 Loss-of-Function; Somatic Loss of the Wild-Type TRIM28 Allele
Wilms Tumor risk factor
mechanism: TRIM28 Tumor Suppressor Loss
Mechanism modules · computed from kb/

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.