GDAP1 - dismech genes

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

Disorder	Relationship	Where the gene appears
Autosomal dominant Charcot-Marie-Tooth disease type 2K	causative germline
Intermediate Charcot-Marie-Tooth Disease	causative germline	mechanism: GDAP1 Loss of Axonal and Schwann-Cell Integrity subtype: RI-CMTA scoped to subtype: RI-CMTA
Charcot-Marie-Tooth Disease Type 2	untyped Causative	mechanism: Impaired Mitochondrial Fission subtype: CMT2K scoped to subtype: CMT2K
Charcot-Marie-Tooth Disease Type 4	untyped Causal	mechanism: GDAP1 Mitochondrial Dynamics Defect subtype: CMT4A scoped to subtype: CMT4A

ClinGen gene–disease validity · snapshot 2026-10-03 · matched to entries by MONDO

An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.

ClinGen disease	MOI	Classification	dismech entry
Charcot-Marie-Tooth disease MONDO:0015626	SD	Definitive 2020-07-28	Charcot-Marie-Tooth Disease not named

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.