Previous symbols: NALP1, SLEV1. Aliases: KIAA0926, DKFZp586O1822, CARD7, NAC, CLR17.1, DEFCAP, VAMAS1.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Familial Cold Autoinflammatory Syndrome | causative germline |
mechanism: NLRP1 inflammasome activation
subtype: NAIAD
scoped to subtype: NAIAD
|
| Toxoplasmosis | susceptibility | |
| Addison's Disease |
untyped
Inflammasome component; variants implicate inflammatory pathways
|
mechanism: Polygenic Susceptibility
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.